АЗИНОКС PLUS for Dogs

Benefits:

•High efficacy and reliability, time-tested

•Broad-spectrum anthelmintic action

•Effective against all developmental stages of roundworms and tapeworms

•Well tolerated by dogs of various breeds and ages

•Has the taste and aroma of fresh meat, which pets enjoy

•Safe for puppies from 3 weeks of age

Composition and Pharmacological Properties:

Each tablet contains the active ingredients: praziquantel – 50 mg and pyrantel pamoate – 150 mg, along with excipients: lactose, potato starch, and a flavoring additive with fresh meat aroma.

The active ingredients provide a broad-spectrum anthelmintic effect against all stages of development of roundworms and tapeworms in dogs, including Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum, Trichuris vulpis, Echinococcus granulosus, Echinococcus multilocularis, Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, and Taenia spp.

Praziquantel – a member of the pyrazinoisoquinoline group, active against gastrointestinal cestodes at all developmental stages. It increases the permeability of parasite cell membranes to calcium ions (Ca²⁺), causing membrane depolarization, muscle contraction, and tegument destruction, leading to parasite death and their elimination from the host. Praziquantel is rapidly absorbed in the gastrointestinal tract, reaching maximum plasma concentration within 60 minutes; it binds to serum proteins (70–80%), is partially metabolized in the liver, excreted back into the intestines, and eliminated mainly through urine (up to 80%) within 24 hours.

Pyrantel pamoate – a member of the pyrimidine group, active against both adult and immature nematodes. Its mechanism involves blocking neuromuscular transmission through sustained depolarization of postsynaptic membranes (cholinergic agonist), disrupting cell membrane permeability, which leads to paralysis and death of parasites. Pyrantel pamoate is poorly absorbed, providing prolonged action against intestinal parasites; it is mostly excreted unchanged in feces (93%).

Storage:

Store the medication in its closed original packaging in a place protected from direct sunlight, at temperatures between 2°C and 25°C. Any unused portion of the tablet should be placed back in the blister and stored under the same conditions until the next use, but no longer than 3 months after opening. Keep out of reach of children.

Shelf Life:

The drug has a shelf life of 3 years from the date of manufacture when stored properly. After opening, it should be used within 3 months. Do not use after the expiration date.

Dosage Form:

Oral tablets with the taste and aroma of fresh meat. The product is available in blister packs of 3 or 6 tablets, individually packaged in a cardboard box with instructions for use and stickers for the veterinary passport